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In patients with CKD Stage 3 and persistent proteinuria already receiving maximal tolerated ACEi or ARB therapy, guideline-directed add-on therapies include SGLT2 inhibitors (e.g., Empagliflozin/Dapagliflozin) or non-steroidal mineralocorticoid receptor antagonists (Finerenone), followed by dihydropyridine calcium channel blockers.
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